Sci-Math Seminar

Speaker: Prof. James G. Fujimoto, MIT

Title: Biomedical imaging using optical coherence tomography

Date: Thu 15 June, 2006
Time: 16:45
Place: Science Building, Room Z42

Abstract:

Optical coherence tomography (OCT) is an emerging imaging modality
which can generate high resolution, cross-sectional images of
microstructure in biological systems.  OCT is analogous to ultrasound
B mode imaging, except that it uses light instead of sound.  Imaging
is performed by measuring the echo time delay of optical
backscattering in the tissue as a function of transverse position.
The penetration depth of OCT imaging is limited by attenuation from
optical scattering to be 2 to 3 mm in most tissues, however, image
resolutions of 1-15 um may be achieved.  OCT functions as a type of
"optical biopsy" to permit the in situ visualization of tissue
microstructure with resolutions approaching that of conventio nal
histopathology.  Imaging can be performed in real time without the
need to remove and process a specimen as in conventional biopsy and
histopathology.  Recent research has enabled dramatic improvements in
resolution as well as imaging speed, enabling three dimensional
visualization of tissue on a micron scale.  OCT is rapidly becoming a
clinical standard in ophthalmology, where it enables imaging of
retinal pathology with unprecedented resolutions.  OCT is also being
developed for many other applications spanning such diverse
applications as cancer detection in endoscopy, intravascular imaging
in cardiology, and functional imaging of the retina and cortex.  This
presentation will discuss OCT technology and applications.

 

 

James G. Fujimoto obtained his bachelors, masters, and doctorate from
the Massachusetts Institute of Technology.  Since 1985 he has been on
the faculty of the Department of Electrical Engineering and Computer
Science at M.I.T. where he is Professor of Electrical Engineering and
Computer Science.  His research interests include the development and
application of femtosecond laser technology and studies of ultrafast
phenomena.  He is also active in biomedical optics, including the
development of optical coherence tomography imaging.  Dr. Fujimoto was
awarded the Baker Award of the National Academy of Sciences in 1990,
the Discover Magazine Award for Technological Innovation in medical
diagnostics in 1999, and was co-recipient of the Rank Prize in
Optoelectronics in 2002.  He was elected to the National Academy of
Engineering in 2001, the American Academy of Arts and Sciences in
2002, and the National Academy of Science in 2006.  Dr. Fujimoto is a
Fellow of the OSA, APS, and IEEE.  He was program co-chair for the
Conference on Lasers and Electro Optics 2002, general co-chair in
2004, and co-chair of the European Conferences on Biomedical Optics in
2005.  Dr. Fujimoto has been general co-chair of the SPIE BIOS
symposium since 2003 and co-chair of the conference Coherence Domain
Optical Methods in Biomedical Science and Clinical Applications since
2000.  Dr. Fujimoto was on the board of directors of the Optical
Society of America from 2000 to 2003.  He is co-founder of Advanc ed
Ophthalmic! Devices , the company that transferred OCT to Carl Zeiss
for ophthalmic imaging and co-founder of LightLabs Imaging, a joint
venture with Carl Zeiss in the area of endoscopic and cardiovascular
imaging that was acquired by Goodman, Ltd. in 2002.

Please visit http://home.ku.edu.tr/~sci-math for a schedule of
upcoming Science -Math seminars at Koc University.